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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CLDN8 Antibody (Center)   

CLDN8 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CLDN8 Antibody (Center) AP9222c
    Western blot analysis of CLDN8 Antibody (Center) (Cat. #AP9222c) in 293 cell line lysates (35ug/lane). CLDN8 (arrow) was detected using the purified Pab.
  • FC - CLDN8 Antibody (Center) AP9222c
    CLDN8 Antibody (Center) (Cat. #AP9222c) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P56748
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 24845 Da
Antigen Region 140-166 aa
Additional Information
Gene ID 9073
Other Names Claudin-8, CLDN8
Target/Specificity This CLDN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-166 amino acids from the Central region of human CLDN8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLDN8 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLDN8
Function Plays a major role in tight junction-specific obliteration of the intercellular space.
Cellular Location Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Note=Localizes to tight junctions in all 3 segments of the epididymis, in the caput found in the lateral margins of principal cells, and in the corpus at the interface between basal and principal cells
Tissue Location Expressed in the epididymis, mainly in the caput segment.
Research Areas
Citations ( 0 )


CLDN8 is components of epithelial cell tight junctions. Tight junctions regulate movement of solutes and ions through the paracellular space and prevent mixing of proteins and lipids in the outer leaflet of the apical and basolateral plasma membrane domains


Kim,S.S.,, Histopathology 54 (5), 633-635 (2009)
Osunkoya,A.O.,, Hum. Pathol. 40 (2), 206-210 (2009)

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$ 295.00
$ 99.00
Cat# AP9222c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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