|Application ||WB, FC, E|
|Calculated MW||27563 Da|
|Antigen Region||176-205 aa|
|Other Names||Tetraspanin-6, Tspan-6, A15 homolog, Putative NF-kappa-B-activating protein 321, T245 protein, Tetraspanin TM4-D, Transmembrane 4 superfamily member 6, TSPAN6, TM4SF6|
|Target/Specificity||This TSPAN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176~205 amino acids from the C-terminal region of human TSPAN6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TSPAN6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2.
Ross,M.T., et.al., Nature 434 (7031), 325-337 (2005)
Clark,H.F., et.al., Genome Res. 13 (10), 2265-2270 (2003)
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