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IPPK Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP9236c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP9236c-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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IPPK Antibody (Center) - Product info | |
| Application | WB, IHC
|
| Primary Accession | Q9H8X2 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 56017 Da |
IPPK Antibody (Center) - Additional info | |
| Gene ID 64768 | |
| Other Names IPPK; C9orf12; Inositol-pentakisphosphate 2-kinase; IPK1 homolog; Inositol-1, 3, 4, 5, 6-pentakisphosphate 2-kinase; Ins(1, 3, 4, 5, 6)P5 2-kinase | |
| Target/Specificity This IPPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336~365 amino acids from the Center region of human IPPK. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions IPPK Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
IPPK Antibody (Center) - Protein Information | |
| Name IPPK | |
| Synonyms C9orf12 | |
| Function Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis | |
| Cellular Location Cytoplasm (By similarity). Nucleus (By similarity) | |
| Tissue Location Ubiquitously expressed, with high expression in heart, brain, testis and placenta | |
IPPK Antibody (Center) - Related products
IPPK Antibody (Center) - Application data
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Western blot analysis of IPPK Antibody (Center) (Cat. #AP9236c) in HL-60 cell line lysates (35ug/lane). IPPK (arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded human testis tissue reacted with IPPK Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
IPPK Antibody (Center) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
IPPK belongs to the IPK1 type 2 family. It phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). IPPK is ubiquitous, with high expression in heart, brain, testis and placenta.
REFERENCES
Verbsky,J. et.al, Nature 429 (6990), 369-374 (2004) Verbsky,J.W., et.al, J. Biol. Chem. 277 (35), 31857-31862 (2002)
