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WDR37 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q9Y2I8 |
| Other Accession | Q8CBE3 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 54665 Da |
| Antigen Region | 426-455 aa |
| Gene ID | 22884 |
|---|---|
| Other Names | WD repeat-containing protein 37, WDR37, KIAA0982 |
| Target/Specificity | This WDR37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-455 amino acids from the C-terminal region of human WDR37. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | WDR37 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | WDR37 |
|---|---|
| Synonyms | KIAA0982 |
| Function | Required for normal ER Ca2+ handling in lymphocytes. Together with PACS1, it plays an essential role in stabilizing peripheral lymphocyte populations. |
| Cellular Location | Cytoplasm. Nucleus Note=Primarily localized in the cytoplasm with the highest concentration in the perinuclear region and in small clusters at the leading edge of the spreading cells. |
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Provided below are standard protocols that you may find useful for product applications.
Background
WDR37 encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes.
References
Yoshida,T.,Int. J. Mol. Med. 25 (4), 649-656 (2010)
Deloukas,P., et.al, Nature 429 (6990), 375-381 (2004)
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