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EFHD2 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP9285b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP9285b-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
EFHD2 Antibody (C-term) - Product info | |
| Application | WB, IHC, FC
|
| Primary Accession | Q96C19 |
| Other Accession | Q4FZY0, Q9D8Y0, A5D7A0 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 26697 Da |
EFHD2 Antibody (C-term) - Additional info | |
| Gene ID 79180 | |
| Other Names EFHD2; SWS1; EF-hand domain-containing protein D2; Swiprosin-1 | |
| Target/Specificity This EFHD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203~232 amino acids from the C-terminal region of human EFHD2. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions EFHD2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
EFHD2 Antibody (C-term) - Protein Information | |
| Name EFHD2 | |
| Synonyms SWS1 | |
| Function May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance (By similarity) | |
| Cellular Location Membrane raft (By similarity). Note=In a mouse immature B-cell line WEHI-231 (By similarity) | |
| Tissue Location Found in lymphocytes; preferentially expressed in CD8+ cells | |
EFHD2 Antibody (C-term) - Related products
AP9285b: EFHD2 Antibody (C-term)
RI11693: EFHD2 predesign siRNA
EFHD2 Antibody (C-term) - Application data
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Western blot analysis of EFHD2 Antibody (C-term) (Cat. #AP9285b) in HL-60 cell line lysates (35ug/lane). EFHD2 (arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded human testis tissue reacted with EFHD2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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EFHD2 Antibody (C-term) (Cat. #AP9285b) flow cytometric analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
EFHD2 Antibody (C-term) - Research Areas
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BACKGROUND
EFHD2 may regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch. This protein controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
REFERENCES
Thylur,R.P., et.al., J. Cell. Biochem. 108 (3), 705-715 (2009) Martins-de-Souza,D., et.al., Eur Arch Psychiatry Clin Neurosci 259 (3), 151-163 (2009) Avramidou,A., et.al., Cell Death Differ. 14 (11), 1936-1947 (2007)
