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EFTUD2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q15029 |
| Other Accession | O08810, Q5F3X4, A4FUD3 |
| Reactivity | Human |
| Predicted | Bovine, Chicken, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 109436 Da |
| Antigen Region | 257-284 aa |
| Gene ID | 9343 |
|---|---|
| Other Names | 116 kDa U5 small nuclear ribonucleoprotein component, Elongation factor Tu GTP-binding domain-containing protein 2, SNU114 homolog, hSNU114, U5 snRNP-specific protein, 116 kDa, U5-116 kDa, EFTUD2, KIAA0031, SNRP116 |
| Target/Specificity | This EFTUD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-284 amino acids from the Central region of human EFTUD2. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | EFTUD2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EFTUD2 |
|---|---|
| Synonyms | KIAA0031, SNRP116 |
| Function | Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (PubMed:28502770, PubMed:28781166, PubMed:28076346, PubMed:29361316, PubMed:30315277, PubMed:29360106, PubMed:29301961, PubMed:30705154, PubMed:25092792). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (PubMed:16723661). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). |
| Cellular Location | Nucleus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
EFTUD2 is component of the U5 snRNP complex required for pre-mRNA splicing.
References
Miele,A., et.al., J. Cell. Biochem. 102 (1), 136-148 (2007)
Koch,H.B., et.al., Cell Cycle 6 (2), 205-217 (2007)
Ewing,R.M., et.al., Mol. Syst. Biol. 3, 89 (2007)
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