|Application ||WB, IHC-P, E|
|Other Accession||Q9JI12, Q9P2U8, A6QLI1|
|Calculated MW||64561 Da|
|Antigen Region||507-535 aa|
|Other Names||Vesicular glutamate transporter 2, VGluT2, Differentiation-associated BNPI, Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter, Solute carrier family 17 member 6, Slc17a6, Dnpi, Vglut2|
|Target/Specificity||This MOUSE VGLU2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 507-535 amino acids from the C-terminal region of mouse VGLU2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MOUSE VGLU2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome|
|Tissue Location||Expressed in brain. Expressed in hippocampal neurons (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
MOUSE VGLU2 mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. This protein may also mediate the transport of inorganic phosphate.
Birgner,C., et.al., Proc. Natl. Acad. Sci. U.S.A. 107 (1), 389-394 (2010)
Renier,N., et.al., PLoS Biol. 8 (3), E1000325 (2010)
Rose,M.F., et.al., Proc. Natl. Acad. Sci. U.S.A. 106 (52), 22462-22467 (2009)
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