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RNH2C Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RNH2C Antibody (Center) AP9303C
    Western blot analysis of RNH2C Antibody (Center) (Cat. #AP9303c) in HL-60 cell line lysates (35ug/lane). RNH2C(arrow) was detected using the purified Pab.
  • FC - RNH2C Antibody (Center) AP9303C
    RNH2C Antibody (Center) (Cat. #AP9303c) flow cytometric analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8TDP1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 17840 Da
Antigen Region 80-108 aa
Additional Information
Gene ID 84153
Other Names Ribonuclease H2 subunit C, RNase H2 subunit C, Aicardi-Goutieres syndrome 3 protein, AGS3, RNase H1 small subunit, Ribonuclease HI subunit C, RNASEH2C, AYP1
Target/Specificity This RNH2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-108 amino acids from the Central region of human RNH2C.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRNH2C Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms AYP1
Function Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
Cellular Location Nucleus.
Tissue Location Widely expressed.
Citations (0)

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RNH2C encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes.


Chon,H.,, Nucleic Acids Res. 37 (1), 96-110 (2009)
Rice,G.,, Am. J. Hum. Genet. 81 (4), 713-725 (2007)
Crow,Y.J.,, Nat. Genet. 38 (8), 910-916 (2006)

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$ 295.00
$ 99.00
Cat# AP9303C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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