|Application ||WB, FC, E|
|Other Accession||Q9JMG6, Q3U1J1, Q17QH7|
|Calculated MW||28278 Da|
|Antigen Region||60-88 aa|
|Other Names||TCF3 fusion partner, INO80 complex subunit F, Protein FB1, TFPT, INO80F|
|Target/Specificity||This TFPT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from the N-terminal region of human TFPT.|
|Precautions||TFPT Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Appears to promote apoptosis in a p53/TP53-independent manner.|
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Provided below are standard protocols that you may find useful for product applications.
TFPT component of the chromatin-remodeling INO80 complex which, in addition to chromatin remodeling implicated in crucial functions such as DNA repair, checkpoint regulation, DNA replication, telomemere maintenance and chromosome segregation. This protein appears to promote apoptosis in a TP53/p53-independent manner.
Jiang,F., et.al., Cancer Lett. 253 (2), 265-272 (2007)
Franchini,C., et.al., Apoptosis 11 (12), 2217-2224 (2006)
Olsen,J.V., et.al., Cell 127 (3), 635-648 (2006)
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