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AKAP8 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP9314b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP9314b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
AKAP8 Antibody (C-term) - Product info | |
| Application | WB, IHC, FC
|
| Primary Accession | O43823 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 76108 Da |
AKAP8 Antibody (C-term) - Additional info | |
| Gene ID 10270 | |
| Other Names AKAP8; AKAP95; A-kinase anchor protein 8; A-kinase anchor protein 95 kDa | |
| Target/Specificity This AKAP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 663~692 amino acids from the C-terminal region of human AKAP8. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions AKAP8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
AKAP8 Antibody (C-term) - Protein Information | |
| Name AKAP8 | |
| Synonyms AKAP95 | |
| Function Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II) | |
| Cellular Location Nucleus matrix. Note=Associated with the nuclear matrix. Redistributed and detached from condensed chromatin during mitosis | |
| Tissue Location Highly expressed in heart, liver, skeletal muscle, kidney and pancreas | |
AKAP8 Antibody (C-term) - Related products
AP9314b: AKAP8 Antibody (C-term)
RI10206: AKAP8 predesign siRNA
BP9314b: AKAP8 Antibody (C-term) Blocking Peptide
AKAP8 Antibody (C-term) - Application data
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Western blot analysis of AKAP8 Antibody (C-term) (Cat. #AP9314b) in HepG2 cell line lysates (35ug/lane). AKAP8 (arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded human testis tissue reacted with AKAP8 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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AKAP8 Antibody (C-term) (Cat. #AP9314b) flow cytometric analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
AKAP8 Antibody (C-term) - Research Areas
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BACKGROUND
AKAP8 are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This protein encodes a member of the AKAP family. The encoded protein is located in the nucleus during interphase and is distinctly redistributed during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA.
REFERENCES
Sugiyama,N., et.al., Mol. Cell Proteomics 6 (6), 1103-1109 (2007) Olsen,J.V., et.al., Cell 127 (3), 635-648 (2006) Olsen,J.V., et.al., Cell 127 (3), 635-648 (2006)
