|Application ||WB, FC, E|
|Calculated MW||24148 Da|
|Antigen Region||109-137 aa|
|Other Names||Tetraspanin-2, Tspan-2, Tetraspan NET-3, TSPAN2|
|Target/Specificity||This TSPAN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-137 amino acids from the Central region of human TSPAN2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TSPAN2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in signalling in oligodendrocytes in the early stages of their terminal differentiation into myelin-forming glia and may also function in stabilizing the mature sheath.|
|Cellular Location||Membrane; Multi-pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
TSPAN2 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
Davila,S., et.al., Genes Immun. 11 (3), 232-238 (2010)
Hemler,M.E. J. Cell Biol. 155 (7), 1103-1107 (2001)
Berditchevski,F. J. Cell. Sci. 114 (PT 23), 4143-4151 (2001)
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