|Application ||WB, IHC-P, IF, E|
|Calculated MW||64618 Da|
|Antigen Region||519-548 aa|
|Other Names||Delta-like protein 3, Drosophila Delta homolog 3, Delta3, DLL3|
|Target/Specificity||This DLL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 519-548 amino acids from the C-terminal region of human DLL3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DLL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).|
|Cellular Location||Membrane; Single-pass type I membrane protein|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
DLL3 encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.
Yerges,L.M. J. Bone Miner. Res. 24 (12), 2039-2049 (2009)
Heuss,S.F. Proc. Natl. Acad. Sci. U.S.A. 105 (32), 11212-11217 (2008)
Maisenbacher,M.K. Hum. Genet. 116 (5), 416-419 (2005)
If you have any additional inquiries please email technical services at email@example.com.