|Application ||WB, IHC-P, FC, E|
|Calculated MW||22763 Da|
|Antigen Region||61-89 aa|
|Other Names||Peptidyl-prolyl cis-trans isomerase C, PPIase C, Cyclophilin C, Rotamase C, PPIC, CYPC|
|Target/Specificity||This PPIC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-89 amino acids from the Central region of human PPIC.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PPIC Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.|
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Provided below are standard protocols that you may find useful for product applications.
PPIC is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to other PPIases, this protein can bind immunosuppressant cyclosporin A.
Vasan,R.S. JAMA 302 (2), 168-178 (2009)
Lim,J. Cell 125 (4), 801-814 (2006)
Trahey,M. Proc. Natl. Acad. Sci. U.S.A. 96 (6), 3006-3011 (1999)
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