ATLA2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | Q8NHH9 |
Other Accession | Q6PA06, Q95LN3 |
Reactivity | Human |
Predicted | Monkey, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 66229 Da |
Antigen Region | 297-326 aa |
Gene ID | 64225 |
---|---|
Other Names | Atlastin-2, 365-, ADP-ribosylation factor-like protein 6-interacting protein 2, ARL-6-interacting protein 2, Aip-2, ATL2, ARL6IP2 |
Target/Specificity | This ATLA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-326 amino acids from the Central region of human ATLA2. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ATLA2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ATL2 |
---|---|
Synonyms | ARL6IP2 |
Function | GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis (PubMed:18270207, PubMed:19665976, PubMed:27619977). |
Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes at endoplasmic reticulum (ER) three-way tubular junctions (PubMed:27619977). |
Tissue Location | Expressed in peripheral tissues (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
ATLA2 is GTPase tethering membranes through formation of trans-homooligomer and mediating homotypic fusion of endoplasmic reticulum membranes. This protein play a role in endoplasmic reticulum tubular network biogenesis.
References
Hu,J. Cell 138 (3), 549-561 (2009)
Rismanchi,N. Hum. Mol. Genet. 17 (11), 1591-1604 (2008)
Abel,A. Neurogenetics 5 (4), 239-243 (2004)
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