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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PLCB1 Antibody (C-term)   

PLCB1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PLCB1 Antibody (C-term) AP9374b
    Western blot analysis of PLCB1 Antibody (C-term) (Cat. #AP9374b) in HL-60 cell line lysates (35ug/lane). PLCB1 (arrow) was detected using the purified Pab.
  • FC - PLCB1 Antibody (C-term) AP9374b
    PLCB1 Antibody (C-term) (Cat. #AP9374b) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NQ66
Other Accession Q9Z1B3, P10894
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 138567 Da
Antigen Region 1148-1176 aa
Additional Information
Gene ID 23236
Other Names 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-1, PLC-154, Phosphoinositide phospholipase C-beta-1, Phospholipase C-I, PLC-I, Phospholipase C-beta-1, PLC-beta-1, PLCB1, KIAA0581
Target/Specificity This PLCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1148-1176 amino acids from the C-terminal region of human PLCB1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPLCB1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLCB1
Synonyms KIAA0581
Function The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Cellular Location Nucleus membrane. Cytoplasm. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes
Research Areas
Citations (0)

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The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.


Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
Woodcock, E.A., et al. J. Mol. Cell. Cardiol. 47(5):676-683(2009)
Zhang, Y., et al. J. Recept. Signal Transduct. Res. 29(1):52-62(2009)

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$ 295.00
$ 99.00
Cat# AP9374b
(40 western blots)
Availability: In Stock
Bulk Size
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