|Application ||WB, IHC-P, FC, E|
|Calculated MW||83208 Da|
|Antigen Region||96-124 aa|
|Other Names||Conserved oligomeric Golgi complex subunit 2, COG complex subunit 2, Component of oligomeric Golgi complex 2, Low density lipoprotein receptor defect C-complementing protein, COG2, LDLC|
|Target/Specificity||This COG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 amino acids from the N-terminal region of human COG2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||COG2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for normal Golgi morphology and function.|
|Cellular Location||Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
COG2 encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes.
Edwards, T.L., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (5), 721-735 (2009)
Luke, M.M., et al. Stroke 40(2):363-368(2009)
Shiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28(1):173-179(2008)
Sohda, M., et al. Traffic 8(3):270-284(2007)
Ungar, D., et al. Trends Cell Biol. 16(2):113-120(2006)
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