|Application ||WB, IHC-P, FC, E|
|Other Accession||Q9EQC9, Q6NXI8|
|Calculated MW||20978 Da|
|Antigen Region||158-185 aa|
|Other Names||CXXC-type zinc finger protein 4, Inhibition of the Dvl and axin complex protein, CXXC4, IDAX|
|Target/Specificity||This CXXC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-185 amino acids from the C-terminal region of human CXXC4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CXXC4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1.|
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Provided below are standard protocols that you may find useful for product applications.
CXXC4 acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1.
Kojima, T., et al. Oncogene 28(2):297-305(2009)
Hino, S., et al. Mol. Cell. Biol. 21(1):330-342(2001)
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