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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   IL31 Antibody (N-term)   

IL31 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - IL31 Antibody (N-term) AP9388a
    Western blot analysis of lysates from K562 cell line and human placenta tissue lysate (from left to right), using IL31 Antibody (N-term)(Cat. #AP9388a). AP9388a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
  • IHC-P - IL31 Antibody (N-term) AP9388a
    Formalin-fixed and paraffin-embedded human testis tissue reacted with IL31 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - IL31 Antibody (N-term) AP9388a
    IL31 Antibody (N-term) (Cat. #AP9388a) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6EBC2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 18205 Da
Antigen Region 13-40 aa
Additional Information
Gene ID 386653
Other Names Interleukin-31, IL-31, IL31
Target/Specificity This IL31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human IL31.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL31 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL31
Function Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.
Cellular Location Secreted.
Tissue Location Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.
Research Areas
Citations (0)

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IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma.


Le Saux, S., et al. J. Biol. Chem. 285(5):3470-3477(2010) Zucchelli, M., et al. Inflamm. Bowel Dis. 15(7):961-962(2009) Gutzmer, R., et al. J. Allergy Clin. Immunol. 123(3):619-625(2009) Zhang, Q., et al. Cytokine Growth Factor Rev. 19 (5-6), 347-356 (2008) : Werfel, T., et al. Chem Immunol Allergy 94, 101-111 (2008) :

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$ 295.00
$ 99.00
Cat# AP9388a
(40 western blots)
Availability: In Stock
Bulk Size
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