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DIRAS1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | O95057 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 22329 Da |
| Antigen Region | 109-136 aa |
| Gene ID | 148252 |
|---|---|
| Other Names | GTP-binding protein Di-Ras1, Distinct subgroup of the Ras family member 1, Ras-related inhibitor of cell growth, Rig, Small GTP-binding tumor suppressor 1, DIRAS1, GBTS1, RIG |
| Target/Specificity | This DIRAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-136 amino acids from the Central region of human DIRAS1. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DIRAS1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DIRAS1 |
|---|---|
| Synonyms | GBTS1, RIG |
| Function | Displays low GTPase activity and exists predominantly in the GTP-bound form. |
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side |
| Tissue Location | Highly expressed in heart and brain. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
DIRAS1 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.
References
Kimura, K., et al. Genome Res. 16(1):55-65(2006)
Kontani, K., et al. J. Biol. Chem. 277(43):41070-41078(2002)
Ellis, C.A., et al. Proc. Natl. Acad. Sci. U.S.A. 99(15):9876-9881(2002)
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