|Application ||WB, IHC-P, FC, E|
|Calculated MW||22329 Da|
|Antigen Region||109-136 aa|
|Other Names||GTP-binding protein Di-Ras1, Distinct subgroup of the Ras family member 1, Ras-related inhibitor of cell growth, Rig, Small GTP-binding tumor suppressor 1, DIRAS1, GBTS1, RIG|
|Target/Specificity||This DIRAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-136 amino acids from the Central region of human DIRAS1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DIRAS1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Displays low GTPase activity and exists predominantly in the GTP-bound form.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side|
|Tissue Location||Highly expressed in heart and brain.|
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Provided below are standard protocols that you may find useful for product applications.
DIRAS1 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.
Kimura, K., et al. Genome Res. 16(1):55-65(2006)
Kontani, K., et al. J. Biol. Chem. 277(43):41070-41078(2002)
Ellis, C.A., et al. Proc. Natl. Acad. Sci. U.S.A. 99(15):9876-9881(2002)
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