|Application ||WB, IHC-P, E|
|Other Accession||Q9Z1A6, Q8VDJ3|
|Calculated MW||141456 Da|
|Antigen Region||764-791 aa|
|Other Names||Vigilin, High density lipoprotein-binding protein, HDL-binding protein, HDLBP, HBP, VGL|
|Target/Specificity||This HDLBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 764-791 amino acids from the Central region of human HDLBP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HDLBP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.|
|Cellular Location||Cytoplasm. Nucleus|
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Provided below are standard protocols that you may find useful for product applications.
High density lipoprotein-binding protein, also known as vigilin, is a 110-kD protein that specifically binds HDL molecules and may function in the removal of excess cellular cholesterol.
Chen, S.N., et al. BMC Med. Genet. 10, 111 (2009)
Zhou, J., et al. RNA 14(9):1773-1781(2008)
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)
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