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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CTSD Antibody (C-term)   

CTSD Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CTSD Antibody (C-term) AP9447b
    Western blot analysis of CTSD Antibody (C-term) (Cat. #AP9447b) in A375, MDA-MB231 cell line lysates (35ug/lane). CTSD (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P07339
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 44552 Da
Antigen Region 377-408 aa
Additional Information
Gene ID 1509
Other Names Cathepsin D, Cathepsin D light chain, Cathepsin D heavy chain, CTSD, CPSD
Target/Specificity This CTSD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-408 amino acids from the C-terminal region of human CTSD.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCTSD Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CPSD
Function Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Cellular Location Lysosome. Melanosome. Secreted, extracellular space. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380).
Tissue Location Expressed in the aorta extrcellular space (at protein level).
Research Areas
Citations (0)

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CTSD encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript.


Christensen, B., et al. J. Biol. Chem. 285(11):7929-7937(2010)
Albayrak, O., et al. J. Gerontol. A Biol. Sci. Med. Sci. 65(3):219-224(2010)
Heinrich, M., et al. EMBO J. 18(19):5252-5263(1999)

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$ 295.00
$ 99.00
Cat# AP9447b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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