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NPY2R Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - NPY2R Antibody (N-term) AP9466a
    Western blot analysis of NPY2R Antibody (N-term) (Cat. #AP9466a) in mouse bladder tissue lysates (35ug/lane). NPY2R (arrow) was detected using the purified Pab.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P49146
Other Accession P97295
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 42731 Da
Antigen Region 19-45 aa
Additional Information
Gene ID 4887
Other Names Neuropeptide Y receptor type 2, NPY2-R, NPY-Y2 receptor, Y2 receptor, NPY2R
Target/Specificity This NPY2R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human NPY2R.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNPY2R Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NPY2R
Function Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra
Research Areas
Citations (0)
citation

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Background

Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.

References

?Shoblock, J.R., et al. Psychopharmacology (Berl.) 208(2):265-277(2010)
?Arnett, D.K., et al. J. Hypertens. 27(8):1585-1593(2009)
?Zhang, J., et al. Zhonghua Liu Xing Bing Xue Za Zhi 30(7):695-698(2009)

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$ 182.50
$ 70.00
Cat# AP9466a
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