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IL26 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - IL26 Antibody (Center) AP9472C
    Western blot analysis of IL26 Antibody (Center) (Cat. #AP9472c) in HL-60 cell line lysates (35ug/lane). IL26 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NPH9
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 19843 Da
Antigen Region 88-115 aa
Additional Information
Gene ID 55801
Other Names Interleukin-26, IL-26, Protein AK155, IL26, AK155
Target/Specificity This IL26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-115 amino acids from the Central region of human IL26.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL26 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL26
Synonyms AK155
Function May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
Cellular Location Secreted.
Tissue Location Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T-cells including Th17 inflammatory T-cells; the expression is significantly increased in serum of patients with Crohn's disease (at protein level).
Research Areas
Citations (0)

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IL26 is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri.


?Siezen, C.L., et al. Pediatr. Infect. Dis. J. 28(4):333-335(2009)
?Silverberg, M.S., et al. Nat. Genet. 41(2):216-220(2009)
?Kantarci, O.H., et al. Arch. Neurol. 65(3):349-357(2008)
?Hor, S., et al. J. Biol. Chem. 279(32):33343-33351(2004)

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Cat# AP9472C
(40 western blots)
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