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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   BTBD10 Antibody (Center)   

BTBD10 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - BTBD10 Antibody (Center) AP9476c
    Western blot analysis of BTBD10 Antibody (Center) (Cat. #AP9476c) in K562 cell line lysates (35ug/lane). BTBD10 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BSF8
Other Accession Q80X66
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53779 Da
Antigen Region 191-218 aa
Additional Information
Gene ID 84280
Other Names BTB/POZ domain-containing protein 10, Glucose metabolism-related protein 1, BTBD10, GMRP1 {ECO:0000303|PubMed:21267538}
Target/Specificity This BTBD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 amino acids from the Central region of human BTBD10.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBTBD10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BTBD10
Synonyms GMRP1 {ECO:0000303|PubMed:21267538}
Function Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and accelerating the growth of pancreatic beta cells.
Cellular Location Nucleus. Cytoplasm {ECO:0000250|UniProtKB:Q80X66}. Note=Colocalizes with KCTD20 in filamentous structures. {ECO:0000250|UniProtKB:Q80X66}
Tissue Location Ubiquitously expressed. Highly expressed in adult brain, testis, aorta and small intestine and weakly expressed in the heart, lung, liver, kidney, pancreas, spleen, thymus, prostate, ovary and colon. Down-regulated in glioma
Research Areas
Citations (0)

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BTBD10 appears to behave as a suppressor of cell death, which includes neuronal cell death related to amyotrophic lateral sclerosis. It may also act as an enhancer of cell growth via its positive regulation of Akt phosphorylation.


?Nawa, M., et al. Cell. Signal. 20(3):493-505(2008)
?Chen, J., et al. Gene 340(1):61-69(2004)

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$ 295.00
$ 99.00
Cat# AP9476c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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