|Application ||WB, E|
|Calculated MW||39333 Da|
|Antigen Region||238-267 aa|
|Other Names||Psychosine receptor, G-protein coupled receptor 65, T-cell death-associated gene 8 protein, GPR65, TDAG8|
|Target/Specificity||This GPR65 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238-267 amino acids from the C-terminal region of human GPR65.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GPR65 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. May have a role in activation- induced cell death or differentiation of T-cells.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Predominantly expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta and peripheral blood leukocytes.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. May have a role in activation-induced cell death or differentiation of T-cells.
Mogi, C., et al. J. Immunol. 182(5):3243-3251(2009)
Ishii, S., et al. J. Biol. Chem. 280(10):9083-9087(2005)
Radu, C.G., et al. Proc. Natl. Acad. Sci. U.S.A. 102(5):1632-1637(2005)
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