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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HS3ST2 Antibody (C-term)   

HS3ST2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HS3ST2 Antibody (C-term) AP9513B
    Western blot analysis of HS3ST2 Antibody (C-term) (Cat. #AP9513b) in Hela, 293 cell line lysates (35ug/lane). HS3ST2 (arrow) was detected using the purified Pab.
  • IHC-P - HS3ST2 Antibody (C-term) AP9513B
    Formalin-fixed and paraffin-embedded human brain tissue reacted with HS3ST2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - HS3ST2 Antibody (C-term) AP9513B
    HS3ST2 Antibody (C-term) (Cat. #AP9513b) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y278
Other Accession Q80W66, Q673U1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 41501 Da
Antigen Region 317-346 aa
Additional Information
Gene ID 9956
Other Names Heparan sulfate glucosamine 3-O-sulfotransferase 2, Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2, 3-OST-2, Heparan sulfate 3-O-sulfotransferase 2, h3-OST-2, HS3ST2, 3OST2
Target/Specificity This HS3ST2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-346 amino acids from the C-terminal region of human HS3ST2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHS3ST2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HS3ST2
Synonyms 3OST2
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in GlcA2S-GlcNS. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location Highly expressed in the brain and weakly expressed in the heart, placenta, lung and skeletal muscle
Research Areas
Citations (0)

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Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity.


Ikeda, M., et al. Biol. Psychiatry 67(3):263-269(2010)
Nat. Genet. 41(7):824-828(2009)
Mochizuki, H., et al. J. Biol. Chem. 283(45):31237-31245(2008)
Lawrence, R., et al. Matrix Biol. 26(6):442-455(2007)
O'Donnell, C.D., et al. Virology 346(2):452-459(2006)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)

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Cat# AP9513B
(40 western blots)
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