|Application ||WB, IHC-P, FC, E|
|Calculated MW||106162 Da|
|Antigen Region||76-103 aa|
|Other Names||Nuclear receptor coactivator 7, 140 kDa estrogen receptor-associated protein, Estrogen nuclear receptor coactivator 1, NCOA7, ERAP140, ESNA1|
|Target/Specificity||This NCOA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-103 amino acids from the N-terminal region of human NCOA7.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NCOA7 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.|
|Tissue Location||Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line|
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Provided below are standard protocols that you may find useful for product applications.
NCOA7 enhances the transcriptional activities of several nuclear receptors. It is involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.
?Arai, H., et al. Oncol. Rep. 19(6):1381-1388(2008)
?Liu, Y., et al. Schizophr. Res. 89 (1-3), 360-361 (2007) :
?Durand, M., et al. BMC Cell Biol. 8, 13 (2007) :
?Mungall, A.J., et al. Nature 425(6960):805-811(2003)
?Ohira, M., et al. Cancer Lett. 197 (1-2), 63-68 (2003) :
?Rushing, S.R., et al. Arch. Biochem. Biophys. 403(2):189-201(2002)
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