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PTPRD Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - PTPRD Antibody (N-term) AP9589A
    Western blot analysis of PTPRD Antibody (N-term) (Cat. #AP9589a) in Hela cell line lysates (35ug/lane). PTPRD (arrow) was detected using the purified Pab.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P23468
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 214760 Da
Antigen Region 343-371 aa
Additional Information
Gene ID 5789
Other Names Receptor-type tyrosine-protein phosphatase delta, Protein-tyrosine phosphatase delta, R-PTP-delta, PTPRD
Target/Specificity This PTPRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-371 amino acids from the N-terminal region of human PTPRD.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTPRD Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTPRD
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Background

PTPRD is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance.

References

?Wallace, M.J., et al. Mol. Cell. Biol. 18(5):2608-2616(1998)
?Pulido, R., et al. Proc. Natl. Acad. Sci. U.S.A. 92(25):11686-11690(1995)
?Pulido, R., et al. J. Biol. Chem. 270(12):6722-6728(1995)
?Krueger, N.X., et al. EMBO J. 9(10):3241-3252(1990)

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Cat# AP9589A
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(40 western blots)
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