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>   home   >   Products   >   Primary Antibodies   >   CBX2 Antibody (N-term)   

CBX2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CBX2 Antibody (N-term) AP9605a
    Western blot analysis of CBX2 Antibody (N-term) (Cat. #AP9605a) in MDA-MB231 cell line lysates (35ug/lane). CBX2 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14781
Other Accession P30658
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 56081 Da
Antigen Region 47-75 aa
Additional Information
Gene ID 84733
Other Names Chromobox protein homolog 2, CBX2
Target/Specificity This CBX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-75 amino acids from the N-terminal region of human CBX2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCBX2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CBX2
Function Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.
Cellular Location Nucleus.
Citations (0)

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CBX2 is a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones.


Katoh-Fukui, Y., et al. Nature 393(6686):688-692(1998)
Gecz, J., et al. Genomics 26(1):130-133(1995)
Pearce, J.J., et al. Development 114(4):921-929(1992)
Paro, R., et al. Proc. Natl. Acad. Sci. U.S.A. 88(1):263-267(1991)

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Cat# AP9605a
(40 western blots)
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