|Application ||WB, E|
|Calculated MW||40924 Da|
|Antigen Region||77-106 aa|
|Other Names||Guanine nucleotide-binding protein G(z) subunit alpha, G(x) alpha chain, Gz-alpha, GNAZ|
|Target/Specificity||This GNAZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the N-terminal region of human GNAZ.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GNAZ Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.|
|Cellular Location||Membrane; Lipid-anchor.|
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Provided below are standard protocols that you may find useful for product applications.
GNAZ is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids.
Bazhin, A.V., et al. Cell. Mol. Life Sci. 67(5):817-828(2010)
Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)
Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
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