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CENPI Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CENPI Antibody (Center) AP9618c
    Western blot analysis of CENPI Antibody (Center) (Cat. #AP9618c) in CEM cell line lysates (35ug/lane). CENPI (arrow) was detected using the purified Pab.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q92674
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 86720 Da
Antigen Region 388-414 aa
Additional Information
Gene ID 2491
Other Names Centromere protein I, CENP-I, FSH primary response protein 1, Follicle-stimulating hormone primary response protein, Interphase centromere complex protein 19, Leucine-rich primary response protein 1, CENPI, FSHPRH1, ICEN19, LRPR1
Target/Specificity This CENPI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 388-414 amino acids from the Central region of human CENPI.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCENPI Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CENPI
Synonyms FSHPRH1, ICEN19, LRPR1
Function Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone.
Cellular Location Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex
Citations (0)

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Background

CENPI is involved in the response of gonadal tissues to follicle-stimulating hormone.

References

Cheeseman, I.M., et al. Mol. Biol. Cell 19(2):587-594(2008)
Izuta, H., et al. Genes Cells 11(6):673-684(2006)
Okada, M., et al. Nat. Cell Biol. 8(5):446-457(2006)

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$ 295.00
$ 99.00
Cat# AP9618c
Size:
Quantity:
(40 western blots)
Availability: In Stock
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