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ECHDC1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NTX5 |
| Other Accession | Q6AYG5 |
| Reactivity | Human, Mouse |
| Predicted | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 33698 Da |
| Antigen Region | 254-283 aa |
| Gene ID | 55862 |
|---|---|
| Other Names | Ethylmalonyl-CoA decarboxylase, Enoyl-CoA hydratase domain-containing protein 1, Methylmalonyl-CoA decarboxylase, MMCD, ECHDC1 |
| Target/Specificity | This ECHDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-283 amino acids from the C-terminal region of human ECHDC1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ECHDC1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ECHDC1 |
|---|---|
| Function | Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading (PubMed:22016388). Acts preferentially on (S)- ethylmalonyl-CoA but has also some activity on the (R)-isomer (By similarity). Also has methylmalonyl-CoA decarboxylase activity at lower level (By similarity). |
| Cellular Location | Cytoplasm, cytosol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ECHDC1 belongs to the enoyl-CoA hydratase/isomerase family. There are two named isoforms.
References
Zheng, W., et al. Cancer Epidemiol. Biomarkers Prev. 18(10):2761-2764(2009)
Menachem, T.D., et al. Fam. Cancer 8(4):399-402(2009)
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