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KCE1L Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KCE1L Antibody (Center) AP9666c
    Western blot analysis of KCE1L Antibody (Center) (Cat. #AP9666c) in NCI-H460 cell line lysates (35ug/lane). KCE1L (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UJ90
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 14993 Da
Antigen Region 67-96 aa
Additional Information
Gene ID 23630
Other Names Potassium voltage-gated channel subfamily E member 1-like protein, AMME syndrome candidate gene 2 protein, KCNE1L, AMMECR2
Target/Specificity This KCE1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of human KCE1L.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKCE1L Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNE5
Synonyms AMMECR2, KCNE1L {ECO:0000303|PubMed:1049
Function Potassium channel ancillary subunit that is essential for generation of some native K(+) currents by virtue of formation of heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits. Functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in heart, skeletal muscle, brain, spinal cord and placenta.
Research Areas
Citations (0)

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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a membrane protein which has sequence similarity to the KCNE1 gene product, a member of the potassium channel, voltage-gated, isk-related subfamily. This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome.


Ravn, L.S., et al. Heart Rhythm 5(3):427-435(2008)
Lundquist, A.L., et al. Genomics 87(1):119-128(2006)
Ravn, L.S., et al. Am. J. Cardiol. 96(3):405-407(2005)
Yang, Y., et al. Am. J. Hum. Genet. 75(5):899-905(2004)
Hofman-Bang, J., et al. Clin. Chim. Acta 345 (1-2), 49-53 (2004)
Piccini, M., et al. Genomics 60(3):251-257(1999)

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Cat# AP9666c
(40 western blots)
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