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SLC25A37 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • IF - SLC25A37 Antibody (C-term) AP9715b
    Immunofluorescent analysis of Hela cells, using SLC25A37 Antibody (C-term) (Cat. #AP9715b). AP9715b was diluted at 1:25 dilution. Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Dylight Fluor® 554 (red) conjugated Phalloidin (red).
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  • WB - SLC25A37 Antibody (C-term) AP9715b
    SLC25A37 Antibody (C-term) (Cat. #AP9715b) western blot analysis in K562 cell line and rat spleen tissue lysates (35ug/lane).This demonstrates the SLC25A37 antibody detected the SLC25A37 protein (arrow).
    detail
  • IHC-P - SLC25A37 Antibody (C-term) AP9715b
    SLC25A37 Antibody (C-term) (Cat. #AP9715b) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SLC25A37 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • FC - SLC25A37 Antibody (C-term) AP9715b
    SLC25A37 Antibody (C-term) (Cat. #AP9715b) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IF, WB, FC, IHC-P, E
Primary Accession Q9NYZ2
Reactivity Human, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 37323 Da
Antigen Region 309-338 aa
Additional Information
Gene ID 51312
Other Names Mitoferrin-1, Mitochondrial iron transporter 1, Mitochondrial solute carrier protein, Solute carrier family 25 member 37, SLC25A37, MFRN, MSCP
Target/Specificity This SLC25A37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-338 amino acids from the C-terminal region of human SLC25A37.
Dilution IF~~1:25
WB~~1:1000
IHC-P~~1:10~50
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSLC25A37 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC25A37
Synonyms MFRN, MSCP
Function Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis.
Cellular Location Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q287T7}; Multi-pass membrane protein
Research Areas
Citations (0)
citation

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Background

SLC25A37 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM].

References

Kaneko, K., et al. FEBS J. 276(5):1370-1382(2009) Haitina, T., et al. Genomics 88(6):779-790(2006) Shaw, G.C., et al. Nature 440(7080):96-100(2006) Li, Q.Z., et al. Mamm. Genome 12(11):830-836(2001)

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$ 365.00
$ 140.00
Cat# AP9715b
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