|Application ||WB, IHC-P, E|
|Other Accession||D4A6D8, Q8K377, A1A4H9|
|Calculated MW||58641 Da|
|Antigen Region||88-117 aa|
|Other Names||Leucine-rich repeat transmembrane neuronal protein 1, LRRTM1|
|Target/Specificity||This LRRTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human LRRTM1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LRRTM1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein|
|Tissue Location||Predominantly expressed in forebrain regions including thalamus and cerebral cortex|
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Provided below are standard protocols that you may find useful for product applications.
LRRTM1 may play a role during the development of specific forebrain structures by influencing neuronal differentiation and connectivity, with a possible role in intracellular trafficking within axons.
Francks, C. Laterality 14(1):11-16(2009)
Crow, T.J., et al. Laterality 14(1):3-10(2009)
McManus, C., et al. Laterality 14(1):1-2(2009)
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