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LRRTM1 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - LRRTM1 Antibody (Center) AP9720c
    Western blot analysis of LRRTM1 Antibody (Center) (Cat. #AP9720c) in mouse brain tissue lysates (35ug/lane). LRRTM1 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - LRRTM1 Antibody (Center) AP9720c
    LRRTM1 Antibody (Center) (Cat. #AP9720c) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LRRTM1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q86UE6
Other Accession D4A6D8, Q8K377, A1A4H9
Reactivity Human, Mouse
Predicted Bovine, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 58641 Da
Antigen Region 88-117 aa
Additional Information
Gene ID 347730
Other Names Leucine-rich repeat transmembrane neuronal protein 1, LRRTM1
Target/Specificity This LRRTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human LRRTM1.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLRRTM1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LRRTM1
Function Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level.
Cellular Location Cell membrane; Single-pass type I membrane protein. Postsynaptic cell membrane; Single-pass type I membrane protein
Tissue Location Predominantly expressed in forebrain regions including thalamus and cerebral cortex.
Research Areas
Citations (0)
citation

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Background

LRRTM1 may play a role during the development of specific forebrain structures by influencing neuronal differentiation and connectivity, with a possible role in intracellular trafficking within axons.

References

Francks, C. Laterality 14(1):11-16(2009)
Crow, T.J., et al. Laterality 14(1):3-10(2009)
McManus, C., et al. Laterality 14(1):1-2(2009)

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$ 365.00
$ 140.00
Cat# AP9720c
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