LRRTM1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q86UE6 |
Other Accession | D4A6D8, Q8K377, A1A4H9 |
Reactivity | Human, Mouse |
Predicted | Bovine, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 58641 Da |
Antigen Region | 88-117 aa |
Gene ID | 347730 |
---|---|
Other Names | Leucine-rich repeat transmembrane neuronal protein 1, LRRTM1 |
Target/Specificity | This LRRTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human LRRTM1. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | LRRTM1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LRRTM1 |
---|---|
Function | Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level. |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Postsynaptic cell membrane; Single-pass type I membrane protein |
Tissue Location | Predominantly expressed in forebrain regions including thalamus and cerebral cortex. |
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Provided below are standard protocols that you may find useful for product applications.
Background
LRRTM1 may play a role during the development of specific forebrain structures by influencing neuronal differentiation and connectivity, with a possible role in intracellular trafficking within axons.
References
Francks, C. Laterality 14(1):11-16(2009)
Crow, T.J., et al. Laterality 14(1):3-10(2009)
McManus, C., et al. Laterality 14(1):1-2(2009)
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