|Application ||WB, IHC-P, E|
|Calculated MW||15240 Da|
|Antigen Region||93-122 aa|
|Other Names||Ly6/PLAUR domain-containing protein 1, Putative HeLa tumor suppressor, PHTS, LYPD1, LYPDC1|
|Target/Specificity||This LYPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the C-terminal region of human LYPD1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LYPD1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha- 4:beta-2-containing nAChRs. May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor|
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Provided below are standard protocols that you may find useful for product applications.
Yu, D.H., et al. Exp. Cell Res. 312(6):865-876(2006)
Choy, K.W., et al. Physiol. Genomics 25(1):9-15(2006)
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