- CITATIONS: 2
|Application ||WB, IHC-P, E|
|Calculated MW||37499 Da|
|Antigen Region||175-204 aa|
|Other Names||Mitochondrial amidoxime-reducing component 1, mARC1, 1---, Molybdenum cofactor sulfurase C-terminal domain-containing protein 1, MOSC domain-containing protein 1, Moco sulfurase C-terminal domain-containing protein 1, MARC1, MOSC1|
|Target/Specificity||This MOSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-204 amino acids from the Central region of human MOSC1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MOSC1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||As a component of an N-hydroxylated prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively.|
|Cellular Location||Mitochondrion outer membrane; Single-pass type II membrane protein. Note=Mitochondrial import is mediated by AA 1-40 and requires ATP|
Provided below are standard protocols that you may find useful for product applications.
Gruenewald, S., et al. J. Med. Chem. 51(24):8173-8177(2008) Anantharaman, V., et al. FEMS Microbiol. Lett. 207(1):55-61(2002)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.