- CITATIONS: 2
|Application ||WB, IHC-P, E|
|Calculated MW||37499 Da|
|Antigen Region||175-204 aa|
|Other Names||Mitochondrial amidoxime-reducing component 1, mARC1, 1---, Molybdenum cofactor sulfurase C-terminal domain-containing protein 1, MOSC domain-containing protein 1, Moco sulfurase C-terminal domain-containing protein 1, MARC1, MOSC1|
|Target/Specificity||This MOSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-204 amino acids from the Central region of human MOSC1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MOSC1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||As a component of an N-hydroxylated prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively.|
|Cellular Location||Mitochondrion outer membrane; Single-pass type II membrane protein. Membrane; Lipid-anchor. Note=Mitochondrial import is mediated by AA 1-40 and requires ATP|
Provided below are standard protocols that you may find useful for product applications.
Gruenewald, S., et al. J. Med. Chem. 51(24):8173-8177(2008) Anantharaman, V., et al. FEMS Microbiol. Lett. 207(1):55-61(2002)
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