HSPA12A Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | O43301 |
Other Accession | Q8K0U4 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 74978 Da |
Antigen Region | 398-427 aa |
Gene ID | 259217 |
---|---|
Other Names | Heat shock 70 kDa protein 12A, HSPA12A, KIAA0417 |
Target/Specificity | This HSPA12A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 398-427 amino acids from the Central region of human HSPA12A. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HSPA12A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HSPA12A |
---|---|
Synonyms | KIAA0417 |
Function | Adapter protein for SORL1, but not SORT1. Delays SORL1 internalization and affects SORL1 subcellular localization. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q8K0U4}. Nucleus {ECO:0000250|UniProtKB:Q8K0U4} |
Tissue Location | Widely expressed with highest levels in brain, kidney and muscle. |
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Provided below are standard protocols that you may find useful for product applications.
References
Starr, J.M., et al. Mech. Ageing Dev. 129(12):745-751(2008)
Harris, S.E., et al. BMC Genet. 8, 43 (2007)
Pongrac, J.L., et al. Biol. Psychiatry 56(12):943-950(2004)
Han, Z., et al. Proc. Natl. Acad. Sci. U.S.A. 100(3):1256-1261(2003)
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