|Application ||WB, IHC-P, FC, E|
|Calculated MW||35367 Da|
|Antigen Region||279-308 aa|
|Other Names||Carbonic anhydrase 6, Carbonate dehydratase VI, Carbonic anhydrase VI, CA-VI, Salivary carbonic anhydrase, Secreted carbonic anhydrase, CA6|
|Target/Specificity||This CA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-308 amino acids from the C-terminal region of human CA6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CA6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Reversible hydration of carbon dioxide. Its role in saliva is unknown.|
|Tissue Location||Major constituent of saliva.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown.
Nishimori, I., et al. Bioorg. Med. Chem. 15(15):5351-5357(2007)
Karhumaa, P., et al. Proc. Natl. Acad. Sci. U.S.A. 98(20):11604-11608(2001)
Breton, S. JOP 2 (4 SUPPL), 159-164 (2001) :
Leinonen, J., et al. J. Histochem. Cytochem. 49(5):657-662(2001)
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