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GPSN2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GPSN2 Antibody (C-term) AP9788b
    Western blot analysis of GPSN2 Antibody (C-term) (Cat. #AP9788b) in A2058 cell line lysates (35ug/lane). GPSN2 (arrow) was detected using the purified Pab.
  • IHC-P - GPSN2 Antibody (C-term) AP9788b
    GPSN2 Antibody (C-term) (Cat. #AP9788b) IHC analysis in formalin fixed and paraffin embedded skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GPSN2 Antibody (C-term) for immunohis??
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NZ01
Other Accession Q64232, Q9CY27, Q3ZCD7
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 36034 Da
Antigen Region 268-295 aa
Additional Information
Gene ID 9524
Other Names Very-long-chain enoyl-CoA reductase, Synaptic glycoprotein SC2, Trans-2, 3-enoyl-CoA reductase, TER, TECR, GPSN2, SC2
Target/Specificity This GPSN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-295 amino acids from the C-terminal region of human GPSN2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGPSN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GPSN2, SC2
Function Catalyzes the last of the four reactions of the long- chain fatty acids elongation cycle. This endoplasmic reticulum- bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Expressed in most tissues tested. Highly expressed in skeletal muscle.
Research Areas
Citations (0)

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Microsomal long and very long chain fatty acid elongation uses malonyl-CoA as the 2-carbon donor and consists of 4 sequential reactions. TER catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA.


Hashmi, G., et al. Transfusion 45(5):680-688(2005)
Moon, Y.A., et al. J. Biol. Chem. 278(9):7335-7343(2003)
Mao, M., et al. Proc. Natl. Acad. Sci. U.S.A. 95(14):8175-8180(1998)

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Cat# AP9788b
(40 western blots)
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