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PATL1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PATL1 Antibody (C-term) AP9796b
    Western blot analysis of PATL1 Antibody (C-term) (Cat. #AP9796b) in HL-60 cell line lysates (35ug/lane). PATL1 (arrow) was detected using the purified Pab.
  • IHC-P - PATL1 Antibody (C-term) AP9796b
    PATL1 Antibody (C-term) (Cat. #AP9796b) IHC analysis in formalin fixed and paraffin embedded skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PATL1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - PATL1 Antibody (C-term) AP9796b
    PATL1 Antibody (C-term) (Cat. #AP9796b) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86TB9
Other Accession B5DF93, Q3TC46
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 86850 Da
Antigen Region 489-518 aa
Additional Information
Gene ID 219988
Other Names Protein PAT1 homolog 1, PAT1-like protein 1, Protein PAT1 homolog b, Pat1b, hPat1b, PATL1
Target/Specificity This PATL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-518 amino acids from the C-terminal region of human PATL1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPATL1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PATL1
Function RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV).
Cellular Location Cytoplasm, P-body. Nucleus. Nucleus, PML body. Nucleus speckle. Note=Predominantly cytoplasmic. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner Enriched in splicing speckles. Localization to nuclear foci and speckles requires active transcription. Excluded from the nucleolus
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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Scheller, N., et al. Biochim. Biophys. Acta 1773(12):1786-1792(2007)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)

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$ 295.00
$ 99.00
Cat# AP9796b
(40 western blots)
Availability: In Stock
Bulk Size
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