|Application ||WB, FC, E|
|Calculated MW||55756 Da|
|Antigen Region||195-224 aa|
|Other Names||Rho GTPase-activating protein 19, Rho-type GTPase-activating protein 19, ARHGAP19|
|Target/Specificity||This RHG19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-224 amino acids from the Central region of human RHG19.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Precautions||RHG19 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.|
|Tissue Location||Strong expression in fetal heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Weak expression in adult pancreas, spleen, thymus, and ovary|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Members of the ARHGAP family, such as ARHGAP19, encode negative regulators of Rho GTPases (see RHOA; MIM 165390), which are involved in cell migration, proliferation, and differentiation, actin remodeling, and G1 cell cycle progression.
Lv, L., et al. DNA Seq. 18(3):184-189(2007)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Deloukas, P., et al. Nature 429(6990):375-381(2004)
Jikuya, H., et al. DNA Res. 10(1):49-57(2003)
If you have any additional inquiries please email technical services at firstname.lastname@example.org.