|Application ||WB, FC, E|
|Calculated MW||53020 Da|
|Antigen Region||240-269 aa|
|Other Names||Cytosolic Fe-S cluster assembly factor NARFL, Iron-only hydrogenase-like protein 1, IOP1, Nuclear prelamin A recognition factor-like protein, Protein related to Narf, NARFL, PRN|
|Target/Specificity||This NARFL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-269 amino acids from the Central region of human NARFL.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NARFL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
Song, D., et al. J. Biol. Chem. 284(51):35297-35307(2009)
Huang, J., et al. Biochem. J. 401(1):341-352(2007)
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Daniels, R.J., et al. Hum. Mol. Genet. 10(4):339-352(2001)
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