|Application ||WB, FC, E|
|Calculated MW||126229 Da|
|Antigen Region||1107-1136 aa|
|Other Names||Protocadherin-17, Protocadherin-68, PCDH17, PCDH68, PCH68|
|Target/Specificity||This PCDH17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1107-1136 amino acids from the C-terminal region of human PCDH17.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PCDH17 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Potential calcium-dependent cell-adhesion protein.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein may play a role in the establishment and function of specific cell-cell connections in the brain.
Biswas, S., et al. Dev. Genes Evol. 219(5):265-271(2009)
Charles, C.A., et al. J. Am. Acad. Dermatol. 59(5):758-771(2008)
Sherwin, J.R., et al. Hum. Reprod. 23(5):1063-1068(2008)
Abrahams, B.S., et al. Proc. Natl. Acad. Sci. U.S.A. 104(45):17849-17854(2007)
Gottlieb, D.J., et al. BMC Med. Genet. 8 SUPPL 1, S9 (2007)
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