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ERP44 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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United States
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Ordering Information
Catalog # Size Availability Price  
AP9842c 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP9842c-ev20 20 ug 100 ul In Stock $ 95.00 Add to cart
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ERP44 Antibody (Center) - Product info

ApplicationWB, IHC, FC
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionQ9BS26
ReactivityHuman
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW46971 Da

ERP44 Antibody (Center) - Additional info

Gene ID 23071
Other Names
ERP44; KIAA0573; TXNDC4; Endoplasmic reticulum resident protein 44; Thioredoxin domain-containing protein 4
Target/Specificity
This ERP44 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112~142 amino acids from the Central region of human ERP44.
Dilution
WB~~1:100~500
IHC~~1:50~100
FC~~1:10~50
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
ERP44 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.

ERP44 Antibody (Center) - Protein Information

Name ERP44
Synonyms KIAA0573, TXNDC4
Function
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum
Cellular Location
Endoplasmic reticulum lumen.

ERP44 Antibody (Center) - Related products

AP9842c: ERP44 Antibody (Center)

RI11841: ERP44 predesign siRNA

DC01757: Human TXNDC4 cDNA Clone

BP9842c: ERP44 Antibody (Center) Blocking Peptide

AT4417a: TXNDC4 Antibody (monoclonal) (M01)

AF2126a: TXNDC4 Antibody

ERP44 Antibody (Center) - Application data

  • ERP44 Antibody (Center) (Cat. #AP9842c) western blot analysis in K562,NCI-H460,HL-60,MDA-MB435,CEM cell line lysates (35ug/lane).This demonstrates the ERP44 antibody detected the ERP44 protein (arrow).

  • ERP44 Antibody (Center) (Cat. #AP9842c) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ERP44 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

  • ERP44 Antibody (Center) (Cat. #AP9842c) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

ERP44 Antibody (Center) - Research Areas

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REFERENCES

Fraldi, A., et al. Hum. Mol. Genet. 17(17):2610-2621(2008) Wang, L., et al. EMBO Rep. 9(7):642-647(2008) Mariappan, M., et al. J. Biol. Chem. 283(10):6375-6383(2008) Anelli, T., et al. EMBO J. 26(19):4177-4188(2007) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)