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GTSE1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GTSE1 Antibody (C-term) AP9882B
    All lanes : Anti-GTSE1 Antibody (C-term) at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: MCF-7 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 77 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IHC-P - GTSE1 Antibody (C-term) AP9882B
    GTSE1 Antibody (C-term) (Cat. #AP9882b) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GTSE1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - GTSE1 Antibody (C-term) AP9882B
    GTSE1 Antibody (C-term) (Cat. #AP9882b) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NYZ3
Other Accession Q8R080
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 76645 Da
Antigen Region 690-717 aa
Additional Information
Gene ID 51512
Other Names G2 and S phase-expressed protein 1, GTSE-1, Protein B99 homolog, GTSE1
Target/Specificity This GTSE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 690-717 amino acids from the C-terminal region of human GTSE1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGTSE1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GTSE1
Function May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression.
Cellular Location Cytoplasm, cytoskeleton. Note=Associated with microtubules
Research Areas
Citations (0)

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GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.


Bublik, D.R., et al. J. Biol. Chem. 285(8):5274-5281(2010)
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
Kapranov, P., et al. Genome Res. 15(7):987-997(2005)
Cheng, J., et al. Science 308(5725):1149-1154(2005)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)

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$ 295.00
$ 99.00
Cat# AP9882B
(40 western blots)
Availability: In Stock
Bulk Size
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