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B3GNT6 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - B3GNT6 Antibody (Center) AP9886c
    Western blot analysis of B3GNT6 Antibody (Center) (Cat. #AP9886c) in mouse brain tissue lysates (35ug/lane). B3GNT6 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - B3GNT6 Antibody (Center) AP9886c
    B3GNT6 Antibody (Center) (Cat. #AP9886c) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the B3GNT6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q6ZMB0
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 42748 Da
Antigen Region 146-173 aa
Additional Information
Gene ID 192134
Other Names UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 6, BGnT-6, Beta-1, 3-Gn-T6, Beta-1, 3-N-acetylglucosaminyltransferase 6, Beta3Gn-T6, 241-, Core 3 synthase, B3GNT6
Target/Specificity This B3GNT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-173 amino acids from the Central region of human B3GNT6.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsB3GNT6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name B3GNT6
Function Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs.
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location Present in stomach and colon (at protein level). Restricted in the stomach, colon and small intestine, where core 3 structure is present.
Research Areas
Citations (0)
citation

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References

Lee, S.H., et al. J. Biol. Chem. 284(25):17157-17169(2009)
Iwai, T., et al. Proc. Natl. Acad. Sci. U.S.A. 102(12):4572-4577(2005)
Iwai, T., et al. J. Biol. Chem. 277(15):12802-12809(2002)

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$ 365.00
$ 140.00
Cat# AP9886c
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