|Application ||WB, IHC-P, E|
|Calculated MW||42748 Da|
|Antigen Region||146-173 aa|
|Other Names||UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 6, BGnT-6, Beta-1, 3-Gn-T6, Beta-1, 3-N-acetylglucosaminyltransferase 6, Beta3Gn-T6, 241-, Core 3 synthase, B3GNT6|
|Target/Specificity||This B3GNT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-173 amino acids from the Central region of human B3GNT6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||B3GNT6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs.|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
|Tissue Location||Present in stomach and colon (at protein level). Restricted in the stomach, colon and small intestine, where core 3 structure is present.|
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Provided below are standard protocols that you may find useful for product applications.
Lee, S.H., et al. J. Biol. Chem. 284(25):17157-17169(2009)
Iwai, T., et al. Proc. Natl. Acad. Sci. U.S.A. 102(12):4572-4577(2005)
Iwai, T., et al. J. Biol. Chem. 277(15):12802-12809(2002)
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