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DCP1B Antibody (center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP9888c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP9888c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
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- Backgrounds
DCP1B Antibody (center) - Product info | |
| Application | WB, FC
|
| Primary Accession | Q8IZD4 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 67723 Da |
DCP1B Antibody (center) - Additional info | |
| Gene ID 196513 | |
| Other Names DCP1B; mRNA-decapping enzyme 1B | |
| Target/Specificity This DCP1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268~298 amino acids from the Central region of human DCP1B. | |
| Dilution WB~~1:100~500WB~~1:1000 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions DCP1B Antibody (center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
DCP1B Antibody (center) - Protein Information | |
| Name DCP1B | |
| Function May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (By similarity) | |
| Cellular Location Cytoplasm. Nucleus (By similarity). | |
DCP1B Antibody (center) - Related products
DCP1B Antibody (center) - Application data
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Western blot analysis of DCP1B Antibody (center) (Cat. #AP9888c) in Ramos cell line lysates (35ug/lane). DCP1B (arrow) was detected using the purified Pab.
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DCP1B Antibody (center) (Cat. #AP9888c) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
DCP1B Antibody (center) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay.
REFERENCES
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006) Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005) Lehner, B., et al. Genome Res. 14(7):1315-1323(2004) Cougot, N., et al. J. Cell Biol. 165(1):31-40(2004)
