HOXA3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | O43365 |
Other Accession | O42368, P02831, O93353, Q08DG7 |
Reactivity | Human |
Predicted | Bovine, Chicken, Mouse, Zebrafish |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 46369 Da |
Antigen Region | 413-440 aa |
Gene ID | 3200 |
---|---|
Other Names | Homeobox protein Hox-A3, Homeobox protein Hox-1E, HOXA3, HOX1E |
Target/Specificity | This HOXA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413-440 amino acids from the C-terminal region of human HOXA3. |
Dilution | WB~~1:1000 IHC-P~~1:100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HOXA3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HOXA3 |
---|---|
Synonyms | HOX1E |
Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.
References
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Chung, N., et al. Mol. Biol. Rep. 36(2):227-235(2009)
Wissmuller, S., et al. Nucleic Acids Res. 34(6):1735-1744(2006)
Manzanares, M., et al. EMBO J. 21(3):365-376(2002)
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