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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PYCR1 Antibody (C-term)   

PYCR1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PYCR1 Antibody (C-term) AP9893b
    PYCR1 Antibody (C-term) (Cat. #AP9893b) western blot analysis in K562,WiDr,HepG2 cell line lysates (35ug/lane).This demonstrates the PYCR1 antibody detected the PYCR1 protein (arrow).
  • IHC-P - PYCR1 Antibody (C-term) AP9893b
    PYCR1 Antibody (C-term) (Cat. #AP9893b) IHC analysis in formalin fixed and paraffin embedded colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PYCR1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - PYCR1 Antibody (C-term) AP9893b
    PYCR1 Antibody (C-term) (Cat. #AP9893b) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32322
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 33361 Da
Antigen Region 291-319 aa
Additional Information
Gene ID 5831
Other Names Pyrroline-5-carboxylate reductase 1, mitochondrial, P5C reductase 1, P5CR 1, PYCR1
Target/Specificity This PYCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human PYCR1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPYCR1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PYCR1
Function Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Involved in the cellular response to oxidative stress.
Cellular Location Mitochondrion.
Research Areas
Citations (0)

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This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion.


Reversade, B., et al. Nat. Genet. 41(9):1016-1021(2009)
Guernsey, D.L., et al. Am. J. Hum. Genet. 85(1):120-129(2009)
Meng, Z., et al. J. Mol. Biol. 359(5):1364-1377(2006)

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$ 295.00
$ 99.00
Cat# AP9893b
(40 western blots)
Availability: In Stock
Bulk Size
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